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Código

Public Class Form1

    Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load

    End Sub

    Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click

        Label18.Text = (Val(TextBox1.Text) + Val(TextBox2.Text) + Val(TextBox3.Text) + Val(TextBox4.Text) + Val(TextBox5.Text) + Val(TextBox6.Text) + Val(TextBox7.Text) + Val(TextBox8.Text) + Val(TextBox9.Text) + Val(TextBox10.Text) + Val(TextBox11.Text) + Val(TextBox12.Text))

        Label19.Text = (Val(TextBox1.Text) + Val(TextBox2.Text) + Val(TextBox3.Text) + Val(TextBox4.Text) + Val(TextBox5.Text) + Val(TextBox6.Text) + Val(TextBox7.Text) + Val(TextBox8.Text) + Val(TextBox9.Text) + Val(TextBox10.Text) + Val(TextBox11.Text) + Val(TextBox12.Text)) / 12

    End Sub

    Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click

        Close()

    End Sub

    Private Sub Button3_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button3.Click

        Label18.Text = ""

        Label19.Text = ""

        TextBox1.Text = ""

        TextBox2.Text = ""

        TextBox3.Text = ""

        TextBox4.Text = ""

        TextBox5.Text = ""

        TextBox6.Text = ""

        TextBox7.Text = ""

        TextBox8.Text = ""

        TextBox9.Text = ""

        TextBox10.Text = ""

        TextBox11.Text = ""

        TextBox12.Text = ""

    End Sub

End Class